TIM3 anticorps (APC)
Aperçu rapide pour TIM3 anticorps (APC) (ABIN2568501)
Antigène
Voir toutes TIM3 (TIM 3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17.
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Purification
- The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Phosphate-buffered aqueous solution, ≤0.09 % Sodium azide, may contain carrier protein/stabilizer, ph7.2.
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Stock
- 4 °C
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Stockage commentaire
- The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
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- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
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Autre désignation
- TIM3
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Classe de substances
- Virus
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Sujet
- The F38-2E2 monoclonal antibody specifically reacts with human T cell immunoglobulin and mucin domain containing protein (TIM3), a transmembrane molecule found on monocytes, macrophages, dendritic cells, and activated T cell types such as Treg, Th1, and Th17. TIM3 can exist in soluble and membrane bound forms and the relevant ligand for the protein is Galectin-9. It plays a role in the creation of immunological tolerances, the secretion of Th1 and Th17 related cytokines, and HIV infection.
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ID gène
- 84868
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UniProt
- Q8TDQ0
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Pathways
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
Antigène
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