CTXB anticorps
Aperçu rapide pour CTXB anticorps (ABIN263565)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Specificité
- Reacts with cholera toxin beta subunit.
-
Attributs du produit
- Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB,VC_1456
-
Purification
- Protein A Sepharose chromatography
-
Pureté
- > 90 % pure (SDS-PAGE)
-
Immunogène
- Purified beta subunit of cholera toxin. Hybridization of Sp2/0 myeloma cells with spleencells from Balb/c mice.
-
Isotype
- IgG2a
-
-
-
-
Indications d'application
-
ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Buffer
- PBS, pH 7.4 containing 0.09 % Sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
Date de péremption
- 12 months
-
-
- CTXB (CtxB Gene Product (CTXB))
-
Autre désignation
- Cholera Enterotoxin Subunit B
-
Sujet
- The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB
-
ID gène
- 2613962
-
UniProt
- P01556
Antigène
-