CTXB anticorps

N° du produit ABIN263565

Détail du produit anti-CTXB anticorps

Antigène: CTXB (CtxB Gene Product (CTXB))

Reactivité: Vibrio cholerae

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTXB est non-conjugé

Application: Enzyme Immunoassay (EIA), Western Blotting (WB)

Specificité: Reacts with cholera toxin beta subunit.

Attributs du produit: Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, ctxB, toxB,VC_1456

Purification: Protein A Sepharose chromatography

Pureté: > 90 % pure (SDS-PAGE)

Immunogène: Purified beta subunit of cholera toxin. Hybridization of Sp2/0 myeloma cells with spleencells from Balb/c mice.

Clone: B040M

Isotype: IgG2a

Information d'application

Indications d'application: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, pH 7.4 containing 0.09 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur CTXB

Antigène: CTXB (CtxB Gene Product (CTXB))

Autre désignation: Cholera Enterotoxin Subunit B (CTXB Produits)

Sujet: The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.Synonyms: Cholera enterotoxin B chain, Cholera enterotoxin gamma chain, Choleragenoid, VC_1456, ctxB, toxB

ID gène: 2613962

UniProt: P01556