PD-1 anticorps (AA 21-167)

N° du produit ABIN263912

Détail du produit anti-PD-1 anticorps

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Épitope: AA 21-167

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects PDCD1.

Attributs du produit: Synonyms: Protein PD-1, hPD-1, PDCD1, Programmed cell death protein 1

Purification: Protein-G affinity chromatography

Immunogène: Recombinant human PDCD1 (21-167aa) purified from E. coli

Clone: 4F12

Isotype: IgG2b

Information d'application

Indications d'application: ELISA. Western blot: 1: 500 (starting dilution) approx. 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: CD279 / PD1 (PDCD1 Produits)

Synonymes: anticorps CD279, anticorps PD-1, anticorps PD1, anticorps SLEB2, anticorps hPD-1, anticorps hPD-l, anticorps Ly101, anticorps Pdc1, anticorps programmed cell death 1, anticorps PDCD1, anticorps Pdcd1

Sujet: PDCD1 is an immunoreceptor that belongs to the immunoglobulin (Ig) superfamily, also known as Programmed Cell Death 1. It is expressed on activated T cell, B cells, myeloid cells and a subset of thymocytes. PDCD1 interacts with expressed PDL1 and PDL2 to inhibit the proliferation and activation of T cells and B cells. Both PDL1 and PDL2 are expressed in a wide variety of normal tissues including heart, lung, placenta, spleen and kidney. PDCD1 might be involved in the regulation of peripheral tolerance and may help prevent autoimmune diseases.Synonyms: PDCD1, Programmed cell death protein 1, Protein PD-1, hPD-1

ID gène: 5133

UniProt: Q15116

Pathways: Cancer Immune Checkpoints