TUBG1 anticorps (AA 434-449)
Aperçu rapide pour TUBG1 anticorps (AA 434-449) (ABIN263999)
Antigène
Voir toutes TUBG1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 434-449
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Specificité
- The antibody TU-32 recognizes an epitope (amino acids 434-449 in human) within C-terminus of gamma-tubulin, a 48 kDa structural constituent of cytoskeleton and microtubule organizing center (MTOC).
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Attributs du produit
- Synonyms: Tubulin gamma-1 chain, Gamma-1-tubulin, GCP-1, Gamma-tubulin complex component 1
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Purification
- Protein A Affinity Chromatography
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Immunogène
- Human gamma-tubulin peptide, amino acids 434-449AA Sequence: EYHAATRPDYISWGTQ
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Isotype
- IgG1
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Indications d'application
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ELISA. Western blot. Immunocytochemistry. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, pH ~7.4 containing 15 mM Sodium Azide as preservative
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoidrepeated freezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- TUBG1 (Tubulin, gamma 1 (TUBG1))
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Autre désignation
- TUBG1 / Tubulin gamma 1
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Sujet
- The gamma-tubulin (TUBG1, relative molecular weight about 48 kDa) is a minor member of tubulin family (less that 0.01 % of tubulin dimer). The γ-tubulin ring structures, however, serve to provide structural primer for initiation of microtubular nucleation and growth, thereby being crutial for microtubule-based cellular processes, above all for mitotic spindle formation. In animal cells, a center of microtubule organization is the centrosome composed of a pair of cylindrical centrioles surrounded by fibrous pericentriolar material containing γ-tubulin. Formation of the mitotic spindle is preceded by duplication of centrosome during S phase. Before mitosis, both centrosomes increase their microtubule nucleation capacity and form two microtuble asters that are pushed apart from each other by the forces of motor proteins associated at the microtubule surface.Synonyms: GCP-1, Gamma-1-tubulin, Gamma-tubulin complex component 1, Tubulin gamma-1 chain
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ID gène
- 7283
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UniProt
- P23258
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Pathways
- Dynamique des Microtubules, M Phase
Antigène
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