TNNI3 anticorps (AA 148-158)
Aperçu rapide pour TNNI3 anticorps (AA 148-158) (ABIN264149)
Antigène
Voir toutes TNNI3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 148-158
-
Specificité
- This antibody reacts with free cardiac troponin I (cTnI). Reacts weakly with cTnI forming complexes with other troponin components. Not affected by phosphorylation. Recognizes an epitope located between amino acid residues 148 and 158 of cTnI. No cross-reactivity with skeletal muscle troponin I.
-
Attributs du produit
- Synonyms: TNNI3, TNNC1
-
Purification
- Protein A chromatography
-
Pureté
- > 90 % pure
-
Immunogène
- Free human cTnI and native human cTn complex
-
Isotype
- IgG1
-
-
-
-
Indications d'application
-
Immunoassay. Immunoprecipitation. Immunohistochemistry. Immunoaffinity purification. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Concentration
- 3.1mg/mL (Sigma protein assay kit)
-
Buffer
- PBS, pH 7.4 containing 0,09 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
-
Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
Shelf life: one year from despatch. -
Date de péremption
- 12 months
-
-
- TNNI3 (Cardiac Troponin I (TNNI3))
-
Autre désignation
- Cardiac Troponin I
-
Sujet
- Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.Synonyms: TNNC1, TNNI3
-
ID gène
- 7137
-
UniProt
- P19429
Antigène
-