SMC2 anticorps (AA 523-768)

N° du produit ABIN264446

Détail du produit anti-SMC2 anticorps

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Épitope: AA 523-768

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SMC2 est non-conjugé

Application: Western Blotting (WB)

Specificité: Recognizes SMC2/CAPE.

Attributs du produit: Synonyms: SMC protein 2, SMC-2, SMC2L1, CAP-E, Chromosome-associated protein E, XCAP-Ehomolog, Structural maintenance of chromosomes protein 2

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from mice immunized with recombinantprotein corresponding to amino acids 523-768 of Human CAP-E and Mouse myeloma cells. Genename: SMC2

Clone: E1M

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1-5 μg/mL. Positive Control/Tissue Expression: HeLa cells.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur SMC2

Antigène: SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))

Autre désignation: SMC2 / CAPE (SMC2 Produits)

Synonymes: anticorps CAP-E, anticorps CAPE, anticorps SMC-2, anticorps SMC2L1, anticorps 5730502P04Rik, anticorps AI255214, anticorps AW545314, anticorps Fin16, anticorps Smc2l1, anticorps fb92e05, anticorps wu:fb92e05, anticorps zeh1628, anticorps zgc:55326, anticorps xcap-e, anticorps SCII, anticorps structural maintenance of chromosomes 2, anticorps structural maintenance of chromosomes 2 L homeolog, anticorps SMC2, anticorps Smc2, anticorps smc2, anticorps smc2.L

Sujet: CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.Synonyms: CAP-E, Chromosome-associated protein E, SMC protein 2, SMC-2, SMC2L1, Structural maintenance of chromosomes protein 2, XCAP-E homolog

ID gène: 10592

UniProt: O95347