ADRA2B anticorps

N° du produit ABIN264463

Cet anticorps Souris Monoclonal détecte spécifiquement ADRA2B dans WB et IHC (fro). Il présente une réactivité envers Rat et Souris.

Aperçu rapide pour ADRA2B anticorps (ABIN264463)

Antigène: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADRA2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 5G10

Détail du produit anti-ADRA2B anticorps

Attributs du produit: Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor

Purification: Purified

Immunogène: Antibody raised to synthetic peptide internal sequence corresponding to the thirdintracellular loop of rat alpha 2b adrenergic receptor.

Isotype: IgG1

Information d'application

Indications d'application: Western blot (1-5 μg/mL). Immunohistochemistry. Positive Control/Tissue Expression: MDCK cells transfected with rat alpha2B adrenergicreceptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur ADRA2B

Antigène: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Autre désignation: alpha-2B Adrenergic Receptor

Sujet: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor

ID gène: 24174

UniProt: P19328

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process