ADRA2B anticorps

N° du produit ABIN264463

Cet anticorps Souris Monoclonal détecte spécifiquement ADRA2B dans WB et IHC (fro). Il présente une réactivité avec des échantillons de Rat et Souris.

Aperçu rapide pour ADRA2B anticorps (ABIN264463)

Antigène: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ADRA2B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 5G10

Détail du produit anti-ADRA2B anticorps

Attributs du produit: Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoreceptor, Alpha-2B adrenoceptor

Purification: Purified

Immunogène: Antibody raised to synthetic peptide internal sequence corresponding to the thirdintracellular loop of rat alpha 2b adrenergic receptor.

Isotype: IgG1

Information d'application

Indications d'application: Western blot (1-5 μg/mL). Immunohistochemistry. Positive Control/Tissue Expression: MDCK cells transfected with rat alpha2B adrenergicreceptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détails sur ADRA2B

Antigène: ADRA2B (Adrenergic, alpha-2B-, Receptor (ADRA2B))

Autre désignation: alpha-2B Adrenergic Receptor

Sujet: The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.Synonyms: ADRA2B, ADRA2L1, ADRA2RL1, Alpha-2B adrenoceptor, Alpha-2B adrenoreceptor

ID gène: 24174

UniProt: P19328

Pathways: EGFR Signaling Pathway, cAMP Metabolic Process