NPDC1
Reactivité: Humain, Souris, Rat
WB, ELISA
Hôte: Lapin
Polyclonal
unconjugated
Indications d'application
Western Blot: 1: 1000. Positive Control: Brain tissue lysate (mouse and rat tested, human not yet tested). Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Buffer
20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing. Shelf life: one year from despatch.
Date de péremption
12 months
Antigène
NPDC1
(Neural Proliferation, Differentiation and Control, 1 (NPDC1))
anticorps AI314472, anticorps NPDC-1, anticorps CAB, anticorps CAB-, anticorps CAB-1, anticorps CAB1, anticorps neural proliferation, differentiation and control, 1, gene 1 L homeolog, anticorps neural proliferation, differentiation and control 1, anticorps neural proliferation, differentiation and control, 1, anticorps npdc1.1.L, anticorps Npdc1, anticorps NPDC1
Sujet
The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1