NPDC1 anticorps

N° du produit ABIN264467

L’anticorps anti-NPDC1 Monoclonal Souris est utilisé pour la détection de NPDC1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour NPDC1 anticorps (ABIN264467)

Antigène: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NPDC1 est non-conjugé

Application: Western Blotting (WB)

Clone: 1-60E-005

Détail du produit anti-NPDC1 anticorps

Specificité: This antibody react to NPDC-1.

Attributs du produit: Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from mice immunized with a syntheticpeptide derived from human NPDC-1 protein and mouse myeloma cells.

Isotype: IgG1

Information d'application

Indications d'application: Western Blot: 1: 1000. Positive Control: Brain tissue lysate (mouse and rat tested, human not yet tested).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at 2-8 °C. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur NPDC1

Antigène: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Autre désignation: NPDC1

Sujet: The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptiona levents mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.Synonyms: NPDC-1, Neural proliferation differentiation and control protein 1

ID gène: 56654

UniProt: Q9NQX5