MMP3 anticorps (C-Term)
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- Antigène Voir toutes MMP3 Anticorps
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
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Épitope
- C-Term
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MMP3 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
- Specificité
- This antibody recognizes Human Matrix Metalloproteinase 3. Other species not tested.
- Attributs du produit
- Synonyms: Stromelysin-1, SL-1, Matrix metalloproteinase-3, Transin-1, MMP3, STMY1
- Purification
- Purified
- Immunogène
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the Cterminus of the human MMP3 protein and mousemyeloma Ag8563 cells.
- Clone
- 1B4
- Isotype
- IgG1
- Top Product
- Discover our top product MMP3 Anticorps primaire
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- Indications d'application
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ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS, 0.08 % Sodium Azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
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The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. - Date de péremption
- 12 months
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- Antigène
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- Autre désignation
- MMP-3 (MMP3 Produits)
- Synonymes
- anticorps CHDS6, anticorps MMP-3, anticorps SL-1, anticorps STMY, anticorps STMY1, anticorps STR1, anticorps SLN-1, anticorps SLN1, anticorps STR-1, anticorps Stmy1, anticorps Str1, anticorps MMP10, anticorps chds6, anticorps mmp-3, anticorps mmp13, anticorps mmp3, anticorps sl-1, anticorps stmy, anticorps stmy1, anticorps str1, anticorps matrix metallopeptidase 3, anticorps matrix metallopeptidase 3 (stromelysin 1, progelatinase), anticorps matrix metallopeptidase 3 L homeolog, anticorps MMP3, anticorps Mmp3, anticorps mmp3.L
- Sujet
- The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including Collagen, gelatin, Fibronectin, Laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.Synonyms: MMP3, Matrix metalloproteinase-3, SL-1, STMY1, Stromelysin-1, Transin-1
- Poids moléculaire
- 50 kDa (Proenzyme)
- ID gène
- 4314
- UniProt
- P08254
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