TIMP2 anticorps

N° du produit ABIN264510

Cet anticorps anti-TIMP2 Monoclonal Souris (Clone 3A4) (ABIN264510) détecte spécifiquement TIMP2 dans WB, IHC (p) et EIA. L’anticorps est réactif avec des échantillons de Humain, Souris, Lapin, Poisson zèbre (Danio rerio), Porc et Poulet.

Aperçu rapide pour TIMP2 anticorps (ABIN264510)

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Reactivité: Humain, Souris, Lapin, Poisson zèbre (Danio rerio), Porc, Poulet

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Clone: 3A4

Détail du produit anti-TIMP2 anticorps

Specificité: This antibody recognizes Matrix Metalloproteinase 2 (TIMP2).

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rabbit, Chicken, Zebrafish, Pig.
Species reactivity (tested):Human.

Attributs du produit: Synonyms: TIMP-2, Tissue inhibitor of metalloproteinases 2, Metalloproteinase inhibitor 2, CSC-21K

Purification: Purified

Immunogène: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with asynthetic peptide derived from the human TIMP-2 protein and mouse myeloma Ag8563cells. Sequence common in mouse, rabbit, chicken, zebrafish and pig.

Isotype: IgG2a

Information d'application

Indications d'application: ELISA. Western Blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections: 1 - 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0,95 mg/mL

Buffer: PBS, 0.08 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur TIMP2

Antigène: TIMP2 (Metalloproteinase Inhibitor 2 (TIMP2))

Autre désignation: TIMP2

Sujet: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases,gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation,branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.Synonyms: CSC-21K, Metalloproteinase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2

Poids moléculaire: 18.5-21 kDa

ID gène: 7077

UniProt: P16035

Pathways: cAMP Metabolic Process