Carboxy Methyl Lysine anticorps (methylated)

N° du produit ABIN264528

Cet anticorps anti-Carboxy Methyl Lysine Polyclonal Chèvre (ABIN264528) détecte spécifiquement Carboxy Methyl Lysine dans EIA et WB.

Aperçu rapide pour Carboxy Methyl Lysine anticorps (methylated) (ABIN264528)

Antigène: Carboxy Methyl Lysine (CML)

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Carboxy Methyl Lysine est non-conjugé

Application: Enzyme Immunoassay (EIA), Western Blotting (WB)

Détail du produit anti-Carboxy Methyl Lysine anticorps

Épitope: methylated

Purification: CML-protein Sepharose affinity chromatography

Immunogène: Carboxymethylated Keyhole Limpet Hemocyanin (CML-KLH). Prepared by the reaction of the protein with glyoxylic acid.

Information d'application

Indications d'application: Western Blot. ELISA: 1: 4,000 - 1: 20,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL (OD280nm, E0.1% = 1.35)

Buffer: 75 mM PBS, pH 7.2 containing 75 mM Sodium chloride and 0.5 mM EDTA and 0.02 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Carboxy Methyl Lysine

Antigène: Carboxy Methyl Lysine (CML)

Autre désignation: Carboxy Methyl Lysine

Classe de substances: Amino Acid

Sujet: Carboxymethyl Lysine is formed by the non enzymatic Schiff base reaction of glucose with proteins, followed by an Amadori rearrangement and oxidation that leaves only a carboxymethyl group attached to the lysine. The levels of CML adducts accumulate over time and have been used as an indicator of both serum glucose levels and oxidative protein damage. Elevated serum CML modified proteins have been associated with diabetes and may contribute to diabetic retinopathy, nephropathy and angiopathy.Synonyms: CML, Carboxymethyl-lysine