PLAU anticorps

N° du produit ABIN264790

Cet anticorps Lapin Polyclonal détecte spécifiquement PLAU dans WB et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour PLAU anticorps (ABIN264790)

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAU est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PLAU anticorps

Specificité: This antibody reacts to Urokinase.

Purification: Protein A Chromatography.

Immunogène: Native human Urokinase.

Information d'application

Indications d'application: ELISA: 1/10,000. Western blot: 1/1,000. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 14.4 mg/mL (OD280 nm, E0.1% = 1.36)

Buffer: 0.05 M Sodium Phosphate, 0.5 M Sodium Chloride, 1 mM EDTA, pH 6.6 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -80 °C

Détails sur PLAU

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Autre désignation: uPA / PLAU

Sujet: Urokinase is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in the Urokinase gene may be associated with late onset Alzheimer disease and also with decreased affinity for fibrin binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg Val bond in plasminogen. The proprotein is cleaved at a Lys Ile bond by plasmin to form a two chain derivative in which a single disulfide bond connects the amino terminal A chain to the catalytically active, carboxy terminal B chain. This two chain derivative is also called HMW uPA (high molecular weight uPA). HMW uPA can be further processed into LMW uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino terminal fragment. LMW uPA is proteolytically active but does not bind to the uPA receptor.Synonyms: U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A

ID gène: 5328

NCBI Accession: NP_001138503

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration