PLAU anticorps
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- Antigène Voir toutes PLAU Anticorps
- PLAU (Plasminogen Activator, Urokinase (PLAU))
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Reactivité
- Humain
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PLAU est non-conjugé
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Application
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- Specificité
- This antibody reacts to Urokinase.
- Purification
- Protein A Chromatography.
- Immunogène
- Native human Urokinase.
- Top Product
- Discover our top product PLAU Anticorps primaire
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- Indications d'application
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ELISA: 1/10,000. Western blot: 1/1,000. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 14.4 mg/mL (OD280 nm, E0.1% = 1.36)
- Buffer
- 0.05 M Sodium Phosphate, 0.5 M Sodium Chloride, 1 mM EDTA, pH 6.6 without preservatives.
- Agent conservateur
- Without preservative
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- -80 °C
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- Antigène
- PLAU (Plasminogen Activator, Urokinase (PLAU))
- Autre désignation
- uPA / PLAU (PLAU Produits)
- Synonymes
- anticorps PLAU, anticorps u-PA, anticorps ATF, anticorps BDPLT5, anticorps QPD, anticorps UPA, anticorps URK, anticorps uPA, anticorps UPAM, anticorps plasminogen activator, urokinase, anticorps urokinase-type plasminogen activator, anticorps PLAU, anticorps CpipJ_CPIJ002131, anticorps CpipJ_CPIJ006543, anticorps CpipJ_CPIJ013396, anticorps CpipJ_CPIJ013623, anticorps Plau
- Sujet
- Urokinase is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in the Urokinase gene may be associated with late onset Alzheimer disease and also with decreased affinity for fibrin binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg Val bond in plasminogen. The proprotein is cleaved at a Lys Ile bond by plasmin to form a two chain derivative in which a single disulfide bond connects the amino terminal A chain to the catalytically active, carboxy terminal B chain. This two chain derivative is also called HMW uPA (high molecular weight uPA). HMW uPA can be further processed into LMW uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino terminal fragment. LMW uPA is proteolytically active but does not bind to the uPA receptor.Synonyms: U-plasminogen activator, Urokinase, Urokinase-type plasminogen activator, Urokinase-type plasminogen activator chain B, Urokinase-type plasminogen activator long chain A, Urokinase-type plasminogen activator short chain A
- ID gène
- 5328
- NCBI Accession
- NP_001138503
- UniProt
- P00749
- Pathways
- Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration
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