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Adenovirus E1A anticorps

L’anticorps Mouton Polyclonal anti-Adenovirus E1A a été validé pour IP. Il convient pour détecter Adenovirus E1A dans des échantillons de Adenovirus.
N° du produit ABIN264902

Aperçu rapide pour Adenovirus E1A anticorps (ABIN264902)

Antigène

Adenovirus E1A (HAdV E1A) (Human Adenovirus E1A (HAdV E1A))

Reactivité

  • 2
  • 2
  • 1
Adenovirus

Hôte

  • 2
  • 2
Mouton

Clonalité

  • 2
  • 2
Polyclonal

Conjugué

  • 4
Cet anticorp Adenovirus E1A est non-conjugé

Application

  • 1
  • 1
Immunoprecipitation (IP)
  • Purification

    Purified

    Immunogène

    GST-EIA fusion protein recognizing a 43kD protein.

    Isotype

    IgG
  • Indications d'application

    Western Blot: 1-10 μg /mL. Positive Control: 293 cells are human embryonic kidney cells that have been transformedwith the adenovirus genes E1A and E1B, which are required for adenovirus propagation. This cell line can be used as a positive control for this antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Buffer

    Phosphate buffered saline with 0.08 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C
  • Antigène

    Adenovirus E1A (HAdV E1A) (Human Adenovirus E1A (HAdV E1A))

    Classe de substances

    Viral Protein

    Sujet

    The early region (E1) of the adenovirus genome, responsible for transforming activity, is localized within the left most 11 % of the viral genome and consists of two transcriptional units E1A and E1B. E1A is sufficient for partial transformation and immortalization of primary cells. E1A gene products are necessary for normal levels of transcription of the other early regions of the adenovirus genome during productive infection and are able to either activate or repress the transcription of specific cellular genes. E1A forms specific complexes with cellular proteins including p105 causing inhibition of the cell cycle inducing arresting function of p105. EIA gene encodes potent onco-proteins that modify the normal transcriptional growth regulation of key cellular genes and thus alter cell cycle control.Synonyms: Adenovirus early region 1 antibody, Control protein E1A antibody, E1A antibody
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