VAMP1 anticorps

N° du produit ABIN264917

L’anticorps Mouton Polyclonal anti-VAMP1 a été validé pour WB et IP. Il convient pour détecter VAMP1 dans des échantillons de Humain et Rat.

Aperçu rapide pour VAMP1 anticorps (ABIN264917)

Antigène: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Reactivité: Humain, Rat

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp VAMP1 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-VAMP1 anticorps

Specificité: This antibody reacts to VAMP 1/2.

Purification: Ammonium Sulfate Precipitation

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 10 μg/mL. Immunoprecipitation: 5 - 15 μg/mL. Positive Control: Rat synaptic vesicles.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.08 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur VAMP1

Antigène: VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))

Autre désignation: VAMP-1 / Synaptobrevin-1

Sujet: Vesicle-associated membrane protein 2 is essential for cAMP-regulated exocytosis. VAMP (also know as synaptobrevin) is part of the synaptic vesicle docking and fusion complex and plays a central role in neuroexocytosis. Two VAMP (vesicle-associated membrane protein) isoforms are expressed in the nervous system and are differently distributed among the specialized parts of the tissue. VAMP-1 and -2 are present in all tissues tested, including kidney, adrenal gland, liver, pancreas, thyroid, heart, and smooth muscle. The two isoforms are differentially expressed in various tissues and their level may depend on differentiation. VAMP-1 is restricted to exocrine pancreas and to kidney tubular cells, whereas VAMP-2 is the predominant isoform present in Langerhans islets and in glomerular cells. Both isoforms show a patchy vesicular intracellular distribution in confocal microscopy. Evidence for the importance of neuronal VAMPproteins in the physiology of all cells is indicated.Synonyms: VAMP-1/2, Vesicle associated membrane protein 1 and 2

ID gène: 6843

NCBI Accession: NP_055046

UniProt: P23763