DAB1 anticorps (N-Term)

N° du produit ABIN264969

Détail du produit anti-DAB1 anticorps

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Épitope: N-Term

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp DAB1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody recognizes Mouse DAB1 (Disabled 1) (N-term). Other species not tested.

Purification: Purified

Immunogène: Recombinant protein corresponding to amino acids 1 - 179 of mouse disabled coupled to a GST fusion protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 1 - 5 μg/mL. Immunoprecipitation: 5 - 10 μg/mL. Positive Control: 293 cells transfected with Dab-1 HA tag.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.08 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur DAB1

Antigène: DAB1 (Disabled Homolog 1 (Drosophila) (DAB1))

Autre désignation: DAB1 (DAB1 Produits)

Synonymes: anticorps AI956902, anticorps C630028C02Rik, anticorps scm, anticorps scr, anticorps scrambler, anticorps yot, anticorps disabled-1, anticorps LOC100232823, anticorps si:dkey-242m13.1, anticorps DAB1, anticorps zgc:136547, anticorps DAB1, reelin adaptor protein, anticorps disabled 1, anticorps disabled homolog 1, anticorps Dab, reelin signal transducer, homolog 1a (Drosophila), anticorps Dab, reelin signal transducer, homolog 1b (Drosophila), anticorps DAB1, anticorps Dab1, anticorps LOC100232823, anticorps dab1a, anticorps dab1b

Sujet: Disruption of the disabled-1 gene (Dab1) results in aberrant migration of neurons during development and disorganization of laminar structures throughout the brain. Dab1 is thought to function as an adaptor molecule in signal transduction processes. It contains a protein-protein interaction (PI) similar to the phosphotyrosine binding domain of the Shc oncoprotein, it is phosphorylated by the Src protein tyrosine kinase, and it binds to SH2 binding domains in a phosphotyrosine dependent manner. Disabled-1 acts downstream of reelin in a signalling pathway.Synonyms: Disabled homolog 1

ID gène: 13131

NCBI Accession: NP_034144

UniProt: P97318