S1PR5 anticorps (C-Term)

N° du produit ABIN264983

L’anticorps anti-S1PR5 Polyclonal Lapin est utilisé pour la détection de S1PR5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour S1PR5 anticorps (C-Term) (ABIN264983)

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-S1PR5 anticorps

Épitope: C-Term

Specificité: This antibody reacts to EDG8.

Purification: Purified

Immunogène: Unique synthetic peptide derived from the C-terminus of the human EDG-8 protein

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL, detects recombinant EDG-8 receptors at 42 kDa, Due to lowexpression of EDG receptors, we recommend use of Pierce Femto Signal substrate forwestern blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur S1PR5

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Autre désignation: EDG-8 / S1P5

Sujet: Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.Synonyms: EDG8, Endothelial differentiation G-protein-coupled receptor 8, S1P receptor 5, S1PR5, SPPR-1, SPPR-2

ID gène: 53637

NCBI Accession: NP_001159687

UniProt: Q9H228