CX3CR1 anticorps (AA 175-189)

N° du produit ABIN265002

Détail du produit anti-CX3CR1 anticorps

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Épitope: AA 175-189

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to CX3CR1.

Purification: Purified

Immunogène: Synthetic peptide corresponding to amino acids 175 to 189 of human CX3CR1 receptor. This sequence is identical in rat and differs by one amino acid in mouse.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0.5 to 1 μg/mL. Detects an approximately 50 kDa band in THP-1 cell lysates.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline solution containing 0.02 % sodium azide as a preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: CX3CR1 / GPR13 (CX3CR1 Produits)

Synonymes: anticorps CCRL1, anticorps CMKBRL1, anticorps CMKDR1, anticorps GPR13, anticorps GPRV28, anticorps V28, anticorps Rbs11, anticorps C-X3-C motif chemokine receptor 1, anticorps chemokine (C-X3-C motif) receptor 1, anticorps CX3C chemokine receptor 1, anticorps CX3CR1, anticorps Cx3cr1, anticorps LOC100559882

Sujet: CX3CR1 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human, mouse, and rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively, (1-4). The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1 (5). Recently, CX3CR1 was found to serve as a coreceptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine (6). CX3CR1 mediates leukocyte migration and adhesion (5). CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

ID gène: 1524

NCBI Accession: NP_001164642

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin