S1PR4 anticorps (C-Term)

N° du produit ABIN265012

Détail du produit anti-S1PR4 anticorps

Antigène: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR4 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody recognizes Human EDG-6 / S1P4 / S1PR4. Other species not tested.

Purification: Purified

Immunogène: Synthetic peptide derived from the C-terminal of the EDG-6 receptor.

Information d'application

Indications d'application: Western Blot: Detects EDG-6 receptors at concentration of 5-10 μg/mL by Western blotusing a human EDG-6 receptor transfected cell line. Detects an approximately 45 kDa bandin Cos cells transfected with full length human EDG-6. Due to low expression of EDGreceptors, we recommend use of Pierce Femto Signal substrate for western blotdevelopment.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS, 0.08 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur S1PR4

Antigène: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Autre désignation: S1PR4 / EDG6 (S1PR4 Produits)

Synonymes: anticorps EDG6, anticorps edg6, anticorps LPC1, anticorps S1P4, anticorps SLP4, anticorps Edg6, anticorps Lpc1, anticorps S1p4, anticorps sphingosine-1-phosphate receptor 4, anticorps sphingosine-1-phosphate receptor 4 S homeolog, anticorps S1PR4, anticorps s1pr4.S, anticorps S1pr4

Sujet: EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs. Recently, the designation of the EDG receptors has been modified to include the ligand for the receptor. Thus, the new designation for the EDG-6 receptor is the sphingosine 1-phosphate receptor-4 (S1P-4).Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

ID gène: 8698

NCBI Accession: NP_003766

UniProt: O95977