SUPT16H anticorps (AA 1-329)
Aperçu rapide pour SUPT16H anticorps (AA 1-329) (ABIN265053)
Antigène
Voir toutes SUPT16H AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-329
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Specificité
- This antibody reacts to FACT complex subunit SPT16.
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Purification
- Purified
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Immunogène
- Recombinant protein consisting of amino acids 1 - 329 of the human SPT16 protein conjugated to GST.
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Isotype
- IgG
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Indications d'application
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Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- SUPT16H (FACT complex subunit SPT16 (SUPT16H))
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Autre désignation
- SUPT16H / FACT140
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Sujet
- SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.Synonyms: Chromatin-specific transcription elongation factor 140 kDa subunit, FACT 140 kDa subunit, FACT complex subunit SPT16, FACTp140, Facilitates chromatin transcription complex subunit SPT16
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ID gène
- 11198
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NCBI Accession
- NP_009123
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UniProt
- Q9Y5B9
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Pathways
- Chromatin Binding
Antigène
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