S1PR4 anticorps

N° du produit ABIN265060

Cet anticorps Lapin Polyclonal détecte spécifiquement S1PR4 dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour S1PR4 anticorps (ABIN265060)

Antigène: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-S1PR4 anticorps

Specificité: This antibody reacts to EDG-6 / S1P4 / S1PR4.

Purification: Purified

Immunogène: Synthetic peptide derived from the intermediate region of the EDG6 (S1P4) protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL, Detects an approximately 42 kDa band on RH7777 cellstransfected with full-length EDG-6. Due to low expression of EDG receptors, we recommenduse of Pierce Femto Signal substrate for western blot development.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur S1PR4

Antigène: S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Autre désignation: S1PR4 / EDG6

Sujet: EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine 1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs.Synonyms: EDG-6, Endothelial differentiation G-protein coupled receptor 6, S1P receptor Edg-6, Sphingosine 1-phosphate receptor 4, Sphingosine 1-phosphate receptor Edg-6

ID gène: 8698

NCBI Accession: NP_003766

UniProt: O95977