SAMD8 anticorps
Aperçu rapide pour SAMD8 anticorps (ABIN265117)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- This antibody reacts to Sphingomyelin synthase-related protein 1.
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Purification
- Purified
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Immunogène
- Full-length recombinant sphingomyelin synthase r fusion protein.
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Indications d'application
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ELISA. Western Blot: 5-10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Buffer
- Phosphate buffered saline with 0.08 % Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
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- SAMD8 (Sterile alpha Motif Domain Containing 8 (SAMD8))
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Autre désignation
- SAMD8 / SMSr
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Sujet
- Sphingomyelin (SM) is a major component of animal plasma membranes. Its production involves the transfer of phosphocholine from phosphatidylcholine and then onto ceramide. This also yields diacylglycerol as a side product. The reaction is catalysed by SM synthase, an important enzyme in the regulation of diacylglycerol and ceramide as anti- and proapoptotic stimuli. SM synthesis occurs in the lumen of the Golgi as well as on or at the cell surface. It is uncertain which SM enzyme forms are present at these differnet cellular locations. Human, mouse and Caenorhabditis elegans genomes each contain at least two different SM synthase (SMS) genes. Human SMS1 is localised to the Golgi, SMS2 resides primarily at the plasma membrane.Synonyms: SAM domain-containing protein 8, Sphingomyelin synthase-related protein 1, Sterile alpha motif domain-containing protein 8
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ID gène
- 142891
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NCBI Accession
- NP_653261
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UniProt
- Q96LT4
Antigène
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