LY86 anticorps (C-Term)

N° du produit ABIN265131

Détail du produit anti-LY86 anticorps

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LY86 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody reacts to Lymphocyte Antigen 86/MD-1.

Purification: Purified

Immunogène: Rabbit polyclonal MD-1 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human MD-1

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0,5 - 1 μg/mL. May cooperate with CD180 and TLR4 to mediate the innate immune response to bacteriallipopolysaccharide (LPS) and cytokine production. Important for efficie nt CD180 cellsurface expression.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur LY86

Antigène: LY86 (Lymphocyte Antigen 86 (LY86))

Autre désignation: LY86 / MD-1 (LY86 Produits)

Synonymes: anticorps MD-1, anticorps MMD-1, anticorps dJ80N2.1, anticorps MD1, anticorps LY86, anticorps lymphocyte antigen 86, anticorps LY86, anticorps Ly86

Sujet: Toll-like receptors (TLRs) are evolutionarily conserved patternrecognition molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The signaling of these TLRs is kept under tight control by the expression of endogenous inhibiting proteins such as RP105, a recently identified homolog of TLR4. This protein, in association with MD-1, interacts with and inhibits the TLR4/MD-2 signaling pathway.. While MD-2 can directly bind to LPS, one of the activating molecules of TLR4, the function of MD -1 is less well-known. It has been suggested however, that the RP105/MD-1 complex influences antibody production mediated by both TLR4/MD-2 and TLR2 receptor complexes.Synonyms: Lymphocyte antigen 86, MD1

ID gène: 9450

NCBI Accession: NP_004262

UniProt: O95711

Pathways: Toll-Like Receptors Cascades