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Claudin 3 anticorps

CLDN3 Reactivité: Humain, Souris, Rat WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN265362
  • Antigène Voir toutes Claudin 3 (CLDN3) Anticorps
    Claudin 3 (CLDN3)
    Reactivité
    • 42
    • 20
    • 14
    • 2
    • 2
    Humain, Souris, Rat
    Hôte
    • 43
    • 3
    Lapin
    Clonalité
    • 42
    • 4
    Polyclonal
    Conjugué
    • 25
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Claudin 3 est non-conjugé
    Application
    • 28
    • 21
    • 17
    • 7
    • 6
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of Claudin-3 protein. (region surrounding Thr204)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity-Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CLDN3 Anticorps primaire
  • Indications d'application
    ELISA: 1/40000-1/60000. Western blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry on Paraffin Sections: 1/50-1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    Claudin 3 (CLDN3)
    Autre désignation
    Claudin-3 / CLDN3 (CLDN3 Produits)
    Synonymes
    anticorps claudin-3, anticorps cpe-r2, anticorps cpetr2, anticorps hrvp1, anticorps rvp1, anticorps CLDN3, anticorps LOC100228090, anticorps C7orf1, anticorps CPE-R2, anticorps CPETR2, anticorps HRVP1, anticorps RVP1, anticorps AI182374, anticorps Cpetr2, anticorps mRVP1, anticorps claudin 3 L homeolog, anticorps claudin 3, anticorps claudin-4-like, anticorps cldn3.L, anticorps cldn3, anticorps CLDN3, anticorps LOC100228090, anticorps Cldn3
    Sujet
    The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specfic regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23.Synonyms: C7orf1, CPE-R2, CPE-Receptor 2, CPETR2, Clostridium perfringens enterotoxin receptor 2, RVP1
    Poids moléculaire
    approx. 25 kDa
    ID gène
    1365
    NCBI Accession
    NP_001297
    UniProt
    O15551
    Pathways
    Hepatitis C
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