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Gastrin anticorps

GAST Reactivité: Humain, Souris, Rat WB, IF, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN265432
  • Antigène Voir toutes Gastrin (GAST) Anticorps
    Gastrin (GAST)
    Reactivité
    • 53
    • 32
    • 28
    • 6
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 55
    • 11
    • 1
    Lapin
    Clonalité
    • 56
    • 11
    Polyclonal
    Conjugué
    • 38
    • 9
    • 8
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Gastrin est non-conjugé
    Application
    • 54
    • 30
    • 25
    • 14
    • 13
    • 13
    • 12
    • 11
    • 7
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificité
    This antibody detects endogenous levels of Gastrin protein. (region surrounding Met90)
    Réactivité croisée (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Pureté
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product GAST Anticorps primaire
  • Indications d'application
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE!
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    Gastrin (GAST)
    Autre désignation
    Gastrin (GAST Produits)
    Synonymes
    anticorps GAS, anticorps Gas, anticorps PPG34, anticorps GAST, anticorps gastrin, anticorps GAST, anticorps Gast
    Sujet
    Gastrin, which is normally formed by mucosal cells in the gastric antrum and by the D cells of the pancreatic islets, is a hormone whose main function is to stimulate secretion of HCl by the gastric mucosa. HCl, in turn, inhibits gastrin formation. Gastrin also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine. Gastrin is regulated by epidermal growth factor in both mice and humans. Gastrin is excreted in excess by pancreatic tumors in the Zollinger- Ellison syndrome. Gastrin maps to human chromosome 17q-21. Gastrin- Releasing Peptide (GRP) stimulates the release of gastrin as well as other gastrointestinal hormones, in addition to acting as an autocrine growth factor for certain cell types. High levels of GRP are found in the human lung just after birth and levels decrease thereafter in parallel with the observed disease in a number of pulmonary neuroendocrine cells. GRP is known to promote lung tumorigenesis in model systems and, interestingly, is induced by retinoic acid. GRP is involved in several functions with the hypothalamus,and is thought to play a role in regulating pituitary hormone secretion. GRP maps to human chromosome 18q21.Synonyms: GAS, GAST
    Poids moléculaire
    approx. 12 kDa
    ID gène
    2520
    NCBI Accession
    NP_000796
    UniProt
    P01350
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