GRM7 anticorps

N° du produit ABIN265440

Détail du produit anti-GRM7 anticorps

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRM7 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of mGluR7 protein. (region surrounding Glu894)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GRM7

Antigène: GRM7 (Glutamate Receptor, Metabotropic 7 (GRM7))

Autre désignation: mGluR7 / GRM7 (GRM7 Produits)

Synonymes: anticorps MGLUR7, anticorps GLUR7, anticorps GPRC1G, anticorps MGLU7, anticorps 6330570A01Rik, anticorps BB176677, anticorps C030018L03, anticorps E130018M02Rik, anticorps Gpr1g, anticorps Gprc1g, anticorps mGluR7, anticorps glutamate metabotropic receptor 7, anticorps glutamate receptor, metabotropic 7, anticorps GRM7, anticorps Grm7

Sujet: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-7, which can interact with PRKCABP, acts as a receptor for glutamate. It is highly expressed in various areas of the brain, but highest levels are detected in cerebellum, cerebral cortex and hippocampus.Synonyms: GPRC1G, MGLUR7, Metabotropic glutamate receptor 7

Poids moléculaire: approx. 100 kDa

ID gène: 2917

NCBI Accession: NP_000835

UniProt: Q14831

Pathways: Sensory Perception of Sound, cAMP Metabolic Process, Feeding Behaviour