Integrin beta 5 anticorps

N° du produit ABIN265481

Détail du produit anti-Integrin beta 5 anticorps

Antigène: Integrin beta 5 (ITGB5)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Integrin beta 5 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody antibody detects endogenous levels of Integrin beta5 protein. (region surrounding Val746)

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Pureté: > 95 % pure by SDS-PAGE

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur Integrin beta 5

Antigène: Integrin beta 5 (ITGB5)

Autre désignation: Integrin beta-5 / ITGB5 (ITGB5 Produits)

Synonymes: anticorps ITGB5, anticorps AA475909, anticorps AI874634, anticorps ESTM23, anticorps [b]-5, anticorps [b]5, anticorps [b]5A, anticorps [b]5B, anticorps beta-5, anticorps beta5, anticorps RGD1563276, anticorps integrin, beta 5, anticorps integrin beta 5, anticorps integrin subunit beta 5, anticorps ITGB5, anticorps Itgb5

Sujet: Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16alpha and 8beta subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors, both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many ,biological processes, including cell growth, differentiation, migration and apoptosis.Synonyms: ITGB-5

Poids moléculaire: approx. 88 kDa

ID gène: 3693

NCBI Accession: NP_002204

UniProt: P18084

Pathways: Integrin Complex