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MMP15 anticorps

MMP15 Reactivité: Humain, Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN265526
  • Antigène Voir toutes MMP15 Anticorps
    MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))
    Reactivité
    • 60
    • 39
    • 21
    • 4
    • 4
    • 4
    • 1
    Humain, Souris
    Hôte
    • 62
    • 2
    Lapin
    Clonalité
    • 62
    • 2
    Polyclonal
    Conjugué
    • 25
    • 6
    • 5
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp MMP15 est non-conjugé
    Application
    • 63
    • 36
    • 29
    • 14
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Specificité
    This antibody detects endogenous levels of MMP-15 protein. (region surrounding Leu646)
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Pureté
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product MMP15 Anticorps primaire
  • Indications d'application
    ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    DO NOT FREEZE!
    Stock
    4 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C.
  • Antigène
    MMP15 (Matrix Metallopeptidase 15 (Membrane-inserted) (MMP15))
    Autre désignation
    MMP-15 (MMP15 Produits)
    Synonymes
    anticorps AI503551, anticorps MT2-MMP, anticorps MTMMP2, anticorps SMCP-2, anticorps matrix metallopeptidase 15, anticorps MMP15, anticorps Mmp15
    Sujet
    The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-9 (also designated 92 kDa type IV collagenase or gelatinase B) has been shown to degrade bone collagens in concert with MMP-1 (also designated interstitial collagenase, fibroblast collagenase or collagenase-1), and cysteine proteases and may play a role in bone osteoclastic resorption. MMP-1 is downregulated by p53, and abnormality of p53 expression may contribute to joint degradation in rheumatoid arthritis by regulating MMP-1 expression.Synonyms: MMP15, MT-MMP 2, MT2-MMP, MT2MMP, MTMMP2, Matrix metalloproteinase-15, Membrane-type matrix metalloproteinase 2, Membrane-type-2 matrix metalloproteinase, SMCP-2
    Poids moléculaire
    approx. 80 kDa
    ID gène
    4324
    NCBI Accession
    NP_002419
    UniProt
    P51511
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