Cet anticorps anti-Ki-67 Monoclonal Rat conjugué à Alexa Fluor 488 (Clone 16A8) (ABIN2657090) détecte spécifiquement Ki-67 dans FACS.
L’anticorps est réactif avec des échantillons de Humain et Souris.
The nuclear protein Ki-67 was first identified by the monoclonal antibody Ki-67, which was generated by immunizing mice with nuclei of the L428 Hodgkin lymphoma cell line. Ki-67 protein plays an essential role in ribosomal RNA transcription and cell proliferation. Expression of Ki-67 occurs during G1, S, G2, and M phase, while in G0 phase the Ki-67 protein is not detectable. Ki-67 is strongly expressed in proliferating cells and has been reported as a prognostic marker in various tumors.
Purification
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 488 under optimal conditions.