XBP-1s anticorps (Alexa Fluor 647)

N° du produit ABIN2657234

Cet anticorps anti-XBP-1s Monoclonal Souris conjugué à Alexa Fluor 647 (Clone 143F) (ABIN2657234) détecte spécifiquement XBP-1s dans FACS et CyTOF. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour XBP-1s anticorps (Alexa Fluor 647) (ABIN2657234)

Antigène: XBP-1s

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Alexa Fluor 647

Application: Flow Cytometry (FACS), Mass Cytometry (CyTOF)

Clone: 143F

Détail du produit

Purification: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG2a

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détail du antigène

Antigène: XBP-1s

Sujet: XBP-1 is a transcription factor containing a bZIP domain. It was first identified because of its ability to bind X-box, a conserved transcriptional element in the promoter of human HLA DR gene. XBP-1 has multiple functions. It controls MHC class II gene regulation and is also essential for differentiation of plasma cells. XBP-1 upregulates as part of the ER stress response, also known as the unfolded protein response. Unspliced XBP-1 is 261 amino acids and migrates on the SDS-PAGE around 33 kD, spliced XBP-1, recognized by clone 143F, is 371 amino acids and migrates around 55 kD.