N-Cadherin anticorps (Alexa Fluor 488)

N° du produit ABIN2657402

Détail du produit anti-N-Cadherin anticorps (Alexa Fluor 488)

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp N-Cadherin est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB), ELISA

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Clone: 8C11

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur N-Cadherin

Antigène: N-Cadherin (CDH2) (Cadherin 2 (CDH2))

Autre désignation: CD325 (CDH2 Produits)

Synonymes: anticorps CD325, anticorps CDHN, anticorps CDw325, anticorps NCAD, anticorps N-cadherin, anticorps cadherin-2, anticorps cdhn, anticorps ncad, anticorps cdw325, anticorps CDH2, anticorps Cadherin-2, anticorps Ncad, anticorps glo, anticorps lyr, anticorps pac, anticorps wu:fb47h04, anticorps cadherin 2, anticorps cadherin 2 S homeolog, anticorps cadherin 2, type 1, N-cadherin (neuronal), anticorps CDH2, anticorps cdh2.S, anticorps cdh2, anticorps Cdh2

Sujet: CD325 (N-cadherin) is a 130 kD, single pass transmembrane protein. Its extracellular region consists of five EC domains and has one cytoplasmic domain. N-cadherin is involved in organogenesis and maintenance of organ architecture by contributing to the sorting of heterogeneous cell types and in the cell adhesion needed to form tissues. N-cadherin is expressed by stem cells, myeloblasts, endothelial cells, and fibroblasts, and also is expressed in neural and muscle tissues and some types of carcinoma cells. CD325 associates with the cytoskeleton trough catenin proteins.

Pathways: Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane