CD45RA anticorps (Alexa Fluor 488)

N° du produit ABIN2657445

Cet anticorps Souris Monoclonal détecte spécifiquement CD45RA dans FACS et ICFC. Il présente une réactivité envers Humain.

Aperçu rapide pour CD45RA anticorps (Alexa Fluor 488) (ABIN2657445)

Antigène: CD45RA

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD45RA est conjugé à/à la Alexa Fluor 488

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: HI100

Détail du produit anti-CD45RA anticorps (Alexa Fluor 488)

Réactivité croisée: Chimpanzé

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur CD45RA

Antigène: CD45RA

Autre désignation: CD45RA

Sujet: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.