CD90.2 / Thy-1.2 anticorps (Alexa Fluor 488)

N° du produit ABIN2657491

L’anticorps Rat Monoclonal anti-CD90.2 / Thy-1.2 a été validé pour FACS, IHC et BR. Il convient pour détecter CD90.2 / Thy-1.2 dans des échantillons de Souris.

Aperçu rapide pour CD90.2 / Thy-1.2 anticorps (Alexa Fluor 488) (ABIN2657491)

Antigène: CD90.2 / Thy-1.2

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD90.2 / Thy-1.2 est conjugé à/à la Alexa Fluor 488

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Blocking Reagent (BR)

Clone: 30-H12

Détail du produit anti-CD90.2 / Thy-1.2 anticorps (Alexa Fluor 488)

Réactivité croisée (Details): Does not react with Thy-1.1 (CD90.1)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur CD90.2 / Thy-1.2

Antigène: CD90.2 / Thy-1.2

Autre désignation: CD90.2

Sujet: CD90.2 is a 25-35 kD immunoglobulin superfamily member also known as Thy1.2. It is expressed on hematopoietic stem cells and neurons, all thymocytes, and peripheral T cells in Thy1.2 bearing mouse strains (Balb/c, CBA/J, C3H/He, C57BL/-, DBA, NZB/-). CD90.2 is a glycosylphosphatidylinositol (GPI)-anchored membrane glycoprotein involved in signal transduction. CD90.2 is involved in costimulation of lymphocyte proliferation and induction of hematopoietic stem cells differentiation. CD90.2 has been shown to interact with CD45. The 30-H12 antibody has been reported to induce Ca2+ flux in thymocytes and, in combination with antibody against the CD3/TCR complex, promote thymocyte apoptosis and inhibit CD3-mediated proliferative responses of mature T lymphocytes.