IKZF2 anticorps (Alexa Fluor 488)

N° du produit ABIN2657510

Cet anticorps anti-IKZF2 est un anticorps Hamster arménien Monoclonal détectant IKZF2 dans FACS. Adapté pour Humain et Souris.

Aperçu rapide pour IKZF2 anticorps (Alexa Fluor 488) (ABIN2657510)

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivité: Humain, Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp IKZF2 est conjugé à/à la Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: 22F6

Détail du produit anti-IKZF2 anticorps (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur IKZF2

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Autre désignation: Helios

Sujet: Helios is a member of the Ikaros family of zinc finger transcription factors. It contains a C-terminal region composed of 2 zinc-finger domains that mediate dimerization between the family members. Helios was originally cloned from a mouse thymoma line. It is mainly expressed in peripheral T cells and thymocytes. It is found at high levels in a subpopulation of regulatory T cells. Helios plays an important role in T cell development and homeostasis. Overexpression of Helios profoundly alters αβ T cell differentiation and activation. It has been determined that silencing of Helios in B cells is critical for maintaining normal B cell function. Helios is also involved in tumor immunity.