IKZF2 anticorps (Alexa Fluor 488)

N° du produit ABIN2657510

Cet anticorps anti-IKZF2 Monoclonal Hamster arménien conjugué à Alexa Fluor 488 (Clone 22F6) (ABIN2657510) détecte spécifiquement IKZF2 dans FACS. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour IKZF2 anticorps (Alexa Fluor 488) (ABIN2657510)

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Reactivité: Humain, Souris

Hôte: Hamster arménien

Clonalité: Monoclonal

Conjugué: Cet anticorp IKZF2 est conjugé à/à la Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: 22F6

Détail du produit anti-IKZF2 anticorps (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur IKZF2

Antigène: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Autre désignation: Helios

Sujet: Helios is a member of the Ikaros family of zinc finger transcription factors. It contains a C-terminal region composed of 2 zinc-finger domains that mediate dimerization between the family members. Helios was originally cloned from a mouse thymoma line. It is mainly expressed in peripheral T cells and thymocytes. It is found at high levels in a subpopulation of regulatory T cells. Helios plays an important role in T cell development and homeostasis. Overexpression of Helios profoundly alters αβ T cell differentiation and activation. It has been determined that silencing of Helios in B cells is critical for maintaining normal B cell function. Helios is also involved in tumor immunity.