IL17F anticorps (Alexa Fluor 488)

N° du produit ABIN2657540

Cet anticorps anti-IL17F Polyclonal Chèvre conjugué à Alexa Fluor 488 (Clone Poly5166) (ABIN2657540) détecte spécifiquement IL17F dans WB. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour IL17F anticorps (Alexa Fluor 488) (ABIN2657540)

Antigène: IL17F (Interleukin 17F (IL17F))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp IL17F est conjugé à/à la Alexa Fluor 488

Application: Western Blotting (WB)

Clone: Poly5166

Détail du produit anti-IL17F anticorps (Alexa Fluor 488)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: Ig Fraction

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur IL17F

Antigène: IL17F (Interleukin 17F (IL17F))

Autre désignation: IL-17F

Sujet: IL-17F is part of the IL-17 cytokine family which consists of at least seven structurally related proteins (IL-17A, B, C, D, E, F, and A/F). IL-17F homodimer adopts a cysteine knot motif formed through the interactions of four cysteines, one of which is responsible for inter-chain bonding. IL-17F is most closely related to IL-17A, sharing 50 % amino acid sequence homology. It is expressed by Th17 cells, along with IL-17A homodimer and IL-17A/F heterodimer. IL-17F has been shown to inhibit endothelial cell angiogenesis and induce increased production of IL-2, TGF-β, and MCP-1, playing a critical role in the regulation of inflammatory reactions.

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity