Panendothelial Cell Antigen anticorps (Alexa Fluor 488)

N° du produit ABIN2657569

L’anticorps anti-Panendothelial Cell Antigen Monoclonal Rat est utilisé pour la détection de Panendothelial Cell Antigen dans des échantillons de Souris. Il a été validé pour FACS, IF et WB.

Aperçu rapide pour Panendothelial Cell Antigen anticorps (Alexa Fluor 488) (ABIN2657569)

Antigène: Panendothelial Cell Antigen

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Alexa Fluor 488

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Western Blotting (WB)

Clone: MECA-32

Détail du produit

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 488 under optimal conditions.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détail du antigène

Antigène: Panendothelial Cell Antigen

Sujet: MECA-32 is a 50-55 kD homodimer glycoprotein primarily expressed on most endothelial cells in the embryonic and the adult mouse tissues, except in the brain and in skeletal and cardiac muscle, where it has more restricted distribution. In skeletal and cardiac muscle, the MECA-32 antigen is confined in small arterioles and venules. But in some conditions, such as inflammation or cardiac transplantation, MECA-32 expression can be induced on some negative-cardiac endothelial cells. In the brain, its expression occurs only in the circumventricular organs and the neurohemal tissues. During embryonic development, MECA-32 antigen is expressed on the brain vasculature up to day 16 of gestation, and disappears at day 17 and after.