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IL-22 anticorps (AA 34-179) (Alexa Fluor 647)

IL22 Reactivité: Souris FACS Hôte: Chèvre Polyclonal Poly5164 Alexa Fluor 647
N° du produit ABIN2657957
  • Antigène Voir toutes IL-22 (IL22) Anticorps
    IL-22 (IL22) (Interleukin 22 (IL22))
    Épitope
    • 21
    • 16
    • 7
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 34-179
    Reactivité
    • 76
    • 46
    • 26
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 66
    • 12
    • 11
    • 10
    Chèvre
    Clonalité
    • 76
    • 22
    • 1
    Polyclonal
    Conjugué
    • 51
    • 17
    • 7
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IL-22 est conjugé à/à la Alexa Fluor 647
    Application
    • 74
    • 47
    • 31
    • 14
    • 13
    • 13
    • 8
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.
    Immunogène
    AA 34-179 (Accession# NM_016971), was expressed in E. coli.
    Clone
    Poly5164
    Isotype
    IgG
    Top Product
    Discover our top product IL22 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C
  • Antigène
    IL-22 (IL22) (Interleukin 22 (IL22))
    Autre désignation
    IL-22 (IL22 Produits)
    Synonymes
    anticorps IL-21, anticorps IL-22, anticorps IL-D110, anticorps IL-TIF, anticorps ILTIF, anticorps TIFIL-23, anticorps TIFa, anticorps zcyto18, anticorps IL-22a, anticorps ILTIFa, anticorps Iltif, anticorps RGD1561292, anticorps interleukin-22, anticorps interleukin 22, anticorps IL22, anticorps il22, anticorps Il22
    Sujet
    IL-22 is a cytokine structurally related to IL-10. Mouse IL-22 consists of 179 amino acids and has a predicted molecular weight of 20 kD. It is secreted primarily by Th17, Th1, Th2, lymphoid tissue inducer cells (LTi), and subsets of natural killer cells. It has been reported that aryl hydrocarbon receptor (AhR) expression is essential for the production of IL-22 by TCRγδ T cells. AhR activation increases Th17 polarization and induces IL-22 production. IL-22 functions by engaging the heterodimeric IL-22 receptor (IL-22R) complex, consisting of two receptor subunits, IL-22R1 and IL-10Rβ. IL-22 acts on nonhematopoietic tissue cells, such as epithelial cells of the digestive and respiratory systems and keratinocytes of the skin. IL-22 is involved in inflammatory processes such as dermal inflammation, psoriasis, inflammatory bowel disease, hepatitis, and Crohn's disease. Moreover, it plays a critical role in mucosal immunity and the wound healing process.
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