MUC1 anticorps (APC)
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- Antigène Voir toutes MUC1 Anticorps
- MUC1 (Mucin 1 (MUC1))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp MUC1 est conjugé à/à la APC
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Application
- Western Blotting (WB), ELISA, Immunoprecipitation (IP)
- Purification
- The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
- Clone
- 16A
- Isotype
- IgG1 lambda
- Top Product
- Discover our top product MUC1 Anticorps primaire
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anti-Mucin 1 (MUC1) (AA 410-525) antibody
MUC1 Reactivité: Souris IHC, WB, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 474-630) antibodyMUC1 Reactivité: Souris IHC, WB, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 66-175) antibodyMUC1 Reactivité: Humain IHC, WB, ELISA, FACS, ICC, Neut Hôte: Souris Monoclonal 3B10B4 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 Reactivité: Humain IHC, StM Hôte: Souris Monoclonal MUC1-520 unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 Reactivité: Humain, Souris IHC, WB, ELISA, IF, FACS, Coat, StM Hôte: Souris Monoclonal MUC1-955 unconjugated
anti-Mucin 1 (MUC1) (AA 1182-1255) antibodyMUC1 Reactivité: Humain IHC, WB Hôte: Lapin Polyclonal unconjugated
anti-Mucin 1 (MUC1) antibodyMUC1 Reactivité: Humain IHC, WB Hôte: Lapin Monoclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1098-1255) antibodyMUC1 Reactivité: Humain IHC, WB, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 404-655) antibodyMUC1 Reactivité: Rat IHC, WB, IP, ICC Hôte: Lapin Polyclonal unconjugated
anti-Mucin 1 (MUC1) (AA 1062-1139) antibodyMUC1 Reactivité: Humain, Souris, Rat IHC, WB, ELISA Hôte: Lapin Polyclonal unconjugated
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- MUC1 (Mucin 1 (MUC1))
- Autre désignation
- CD227 (MUC1 Produits)
- Synonymes
- anticorps CA 15-3, anticorps CD227, anticorps EMA, anticorps H23AG, anticorps KL-6, anticorps MAM6, anticorps MCKD1, anticorps MUC-1, anticorps MUC-1/SEC, anticorps MUC-1/X, anticorps MUC1/ZD, anticorps PEM, anticorps PEMT, anticorps PUM, anticorps Muc-1, anticorps mucin 1, cell surface associated, anticorps mucin 1, transmembrane, anticorps MUC1, anticorps Muc1
- Sujet
- Mucin-1 (MUC-1), cell surface associated or polymorphic epithelia mucin, is a 500-1000 kD proteoglycan expressed by activated T cells, mucosal epithelial cells, and aberrantly expressed on most breast cancers. In normal cells, CD227 is heavily glycosylated, whereas in cancerous cells, the glycosylation is incomplete and premature sialation is also observed. The protein is anchored to the apical surface of the epithelial cell and functions as a lubricant to keep the cell hydrated and to protect against pathogens. It can also function as a signaling molecule by forming a MUC-1/SOS1/GrB2 complex. MUC-1 can interact with cancer antigens such as Her2/neu.
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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