IL33RA anticorps (APC)

N° du produit ABIN2658349

L’anticorps Rat Monoclonal anti-IL33RA a été validé pour IHC et ELISA (Capture). Il convient pour détecter IL33RA dans des échantillons de Souris.

Aperçu rapide pour IL33RA anticorps (APC) (ABIN2658349)

Antigène: IL33RA (Interleukin 33 Receptor alpha (IL33RA))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL33RA est conjugé à/à la APC

Application: Immunohistochemistry (IHC), ELISA (Capture)

Clone: DIH9

Détail du produit anti-IL33RA anticorps (APC)

Purification: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IL33RA

Antigène: IL33RA (Interleukin 33 Receptor alpha (IL33RA))

Autre désignation: IL-33R alpha

Sujet: IL-33Rα, also known as ST2 or IL-1RL1, is a member of the Toll/IL-1 receptor family. It binds IL-33 and is structurally similar to IL-1R1. Two forms of the protein exist - a soluble form known as ST2 and a membrane anchored form known as ST2L. The membrane form is expressed by Th2 cells and bone marrow derived mast cells, whereas the soluble form is expressed by serum-stimulated fibroblasts. Blocking with anti-ST2 antibodies has been shown to alleviate experimental arthritis and airway inflammation. The IL-33-ST2 axis has been reported to be important across a range of diseases including asthma, allergies, and cardiac disease.