NCR3 anticorps (APC)

N° du produit ABIN2658623

Cet anticorps anti-NCR3 est un anticorps Souris Monoclonal détectant NCR3 dans FACS et ICFC. Adapté pour Humain.

Aperçu rapide pour NCR3 anticorps (APC) (ABIN2658623)

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NCR3 est conjugé à/à la APC

Application: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Clone: P30-15

Détail du produit anti-NCR3 anticorps (APC)

Attributs du produit: The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is a type I transmembrane protein, member of the natural cytotoxicity receptor family that contains one immunoglobulin-like domain. NKp30 has an apparent molecular weight of 30 kD and six isoforms are produced by alternative splicing. NKp30 is expressed on resting and activated NK cells. NKp30 enhances NK cell cytolysis of tumor cellts that are deficient in MHC class I molecules. NKp30 has been shown to associate with CD59 and TCRζ. The p30-15 antibody against human NKp30 has been shown to be useful for flow cytometry, stimulation of human NK cells via NKp30 in a redirected lysis assay, and blocking of NKp30 function in solution.

Purification: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur NCR3

Antigène: NCR3 (Natural Cytotoxicity Triggering Receptor 3 (NCR3))

Autre désignation: CD337

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process