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PD-1 anticorps (Biotin)

PDCD1 Reactivité: Souris ICFC Hôte: Rat Monoclonal 29F-1A12 Biotin
N° du produit ABIN2660833
  • Antigène Voir toutes PD-1 (PDCD1) Anticorps
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Reactivité
    • 140
    • 82
    • 25
    • 5
    • 3
    • 1
    Souris
    Hôte
    • 73
    • 70
    • 33
    • 12
    • 9
    • 3
    • 1
    Rat
    Clonalité
    • 142
    • 56
    • 2
    Monoclonal
    Conjugué
    • 91
    • 15
    • 13
    • 12
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PD-1 est conjugé à/à la Biotin
    Application
    • 128
    • 56
    • 43
    • 38
    • 34
    • 17
    • 13
    • 13
    • 13
    • 10
    • 10
    • 9
    • 9
    • 8
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Intracellular Flow Cytometry (ICFC)
    Purification
    The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
    Clone
    29F-1A12
    Isotype
    IgG2a kappa
    Top Product
    Discover our top product PDCD1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Protect from prolonged exposure to light. Do not freeze.
    Stock
    4 °C
    Stockage commentaire
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Antigène
    PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
    Autre désignation
    CD279 (PDCD1 Produits)
    Synonymes
    anticorps CD279, anticorps PD-1, anticorps PD1, anticorps SLEB2, anticorps hPD-1, anticorps hPD-l, anticorps Ly101, anticorps Pdc1, anticorps programmed cell death 1, anticorps PDCD1, anticorps Pdcd1
    Sujet
    CD279, also known as programmed death-1 (PD-1), is a 50-55 kD glycoprotein belonging to the CD28 family of the Ig superfamily. PD-1 is expressed on activated splenic T and B cells and thymocytes. It is induced on activated myeloid cells as well. PD-1 is involved in lymphocyte clonal selection and peripheral tolerance through binding its ligands, B7-H1 (PD-L1) and B7-DC (PD-L2). It has been reported that PD-1 and PD-L1 interactions are critical to positive selection and play a role in shaping the T cell repertoire. PD-L1 negative costimulation is essential for prolonged survival of intratesticular islet allografts.
    Pathways
    Cancer Immune Checkpoints
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