IFNGR1 anticorps (Biotin)

N° du produit ABIN2660913

Détail du produit anti-IFNGR1 anticorps (Biotin)

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Reactivité: Souris

Hôte: Hamster

Clonalité: Monoclonal

Conjugué: Cet anticorp IFNGR1 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.

Clone: 2E2

Isotype: IgG

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur IFNGR1

Antigène: IFNGR1 (Interferon gamma Receptor 1 (IFNGR1))

Autre désignation: CD119 (IFNGR1 Produits)

Synonymes: anticorps CD119, anticorps IFNGR, anticorps IFN-gammaR, anticorps Ifgr, anticorps Ifngr, anticorps Nktar, anticorps IFNGR1, anticorps MGC129098, anticorps ifngr1, anticorps MGC194858, anticorps MGC194873, anticorps zgc:194858, anticorps cd119, anticorps ifngr, anticorps DKFZp469K1232, anticorps interferon gamma receptor 1, anticorps cytokine receptor family member B17, anticorps IFNGR1, anticorps Ifngr1, anticorps crfb17, anticorps ifngr1

Sujet: CDw119 is a 90 kD immunoglobulin superfamily member, also known as IFN-γRα chain. It is a class II cytokine receptor family member that serves as a IFN-γ-binding chain associated with the IFN-γ β chain also known as AF-1. In addition to ligand binding, CDw119 participates in ligand trafficking. CDw119 is expressed on T and B cells, NK cells, fibroblasts, endothelial, and epithelial cells. Binding of IFN-γ induces receptor dimerization, internalization, Jak1 and Jak2 protein kinase activation and, ultimately, STAT1 activation. IFN-γ initiates and regulates a variety of immune responses.

Pathways: Interferon-gamma Pathway