CXCR1 anticorps (FITC)

N° du produit ABIN2661541

Détail du produit anti-CXCR1 anticorps (FITC)

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CXCR1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.

Clone: 8F1-CXCR1

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CXCR1

Antigène: CXCR1 (Chemokine (C-X-C Motif) Receptor 1 (CXCR1))

Autre désignation: CD181 (CXCR1 Produits)

Synonymes: anticorps C-C, anticorps C-C-CKR-1, anticorps CD128, anticorps CD181, anticorps CDw128a, anticorps CKR-1, anticorps CMKAR1, anticorps IL8R1, anticorps IL8RA, anticorps IL8RBA, anticorps Il8ra, anticorps CXCR-1, anticorps IL-8RA, anticorps CXCR2, anticorps IL8RB, anticorps cxcr1, anticorps cxcr2, anticorps C-X-C motif chemokine receptor 1, anticorps chemokine (C-X-C motif) receptor 1, anticorps C-X-C chemokine receptor type 1, anticorps C-X-C motif chemokine receptor 1 S homeolog, anticorps CXCR1, anticorps Cxcr1, anticorps LOC100461947, anticorps cxcr1.S

Sujet: CXCR1 is a 67-70 kD seven-transmembrane protein, also known as IL-8 receptor A (IL-8RA), CD181, and CDw128a. It is a CXC chemokine receptor that belongs to the G protein-coupled receptor (CPCR) family. CXCR1 is expressed as homodimer or heterodimer with CXCR2 and found on granulocytes, NK cells, subset of T lymphocytes, mast cells, monocytes, endothelial cells, megakarocytes, and oligodendrocytes. The expression level of CXCR1 on monocytes is lower than that of CXCR2. CXCR1 mediates neutrophil activation and chemotaxis, megakaryocytic proliferation, and angiogenesis via binding its ligands including IL-8(CXCL8), NAP-2(CXCL7), GCP-2(CXCL6), and GRO-α(CXCL1).

Pathways: cAMP Metabolic Process