BST2 anticorps (Pacific Blue)

N° du produit ABIN2662253

L’anticorps Rat Monoclonal anti-BST2 a été validé pour FACS, IHC, IP et CyTOF. Il convient pour détecter BST2 dans des échantillons de Souris.

Aperçu rapide pour BST2 anticorps (Pacific Blue) (ABIN2662253)

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp BST2 est conjugé à/à la Pacific Blue

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Cytometry by Time of Flight (CyTOF)

Clone: 927

Détail du produit anti-BST2 anticorps (Pacific Blue)

Purification: The antibody was purified by affinity chromatography, and conjugated with Pacific Blue™ under optimal conditions. The solution is free of unconjugated Pacific Blue™.

Isotype: IgG2b kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur BST2

Antigène: BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))

Autre désignation: CD317

Sujet: CD317, known as BST2, tetherin, HM1.2 antigen, bone marrow stromal antigen 2, or PDCA-1, is type II transmembrane glycoprotein with a molecular mass of 29-33 kD. It is predominantly expressed on Type I IFN-producing cells (IPCs) in naive mice, but is up-regulated on most cell types following stimulation with type I IFNs and IFN-gamma. It is highly expressed on terminally differentiated normal plasmacytoid dendritic cells and some tumor cells, such as multiple myeloma, renal cell carcinoma, and melanoma cells. BST2 is a recently identified, IFN-induced cellular response factor that blocks release of HIV-1 and other retroviruses from infected cells. BST2 has been found to be the natural ligand of ILT7 in human model.

Pathways: Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response