Allergin-1 anticorps (PE)

N° du produit ABIN2662383

Cet anticorps Souris Monoclonal détecte spécifiquement Allergin-1 dans ELISA (Capture). Il présente une réactivité avec des échantillons de Souris.

Aperçu rapide pour Allergin-1 anticorps (PE) (ABIN2662383)

Antigène: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Allergin-1 est conjugé à/à la PE

Application: ELISA (Capture)

Clone: TX83

Détail du produit anti-Allergin-1 anticorps (PE)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur Allergin-1

Antigène: Allergin-1 (MILR1) (Mast Cell Immunoglobulin-Like Receptor 1 (MILR1))

Autre désignation: Allergin-1

Sujet: Allergin-1, also known as mast cell Ag-32, is a 60 kD single pass transmembrane protein. It contains one Ig-like C2-type (immunoglobulin-like) domain in the extracellular region and one immunoreceptor tyrosine-based inhibitory motif (ITIM)-like domain in the cytoplasmic region. Allergin-1 is expressed on mast cells, dendritic cells, and macrophages as well as at low levels on neutrophils. After tyrosine phosphorylation, allergin-1 recruits PTPN6, PTPN11, and INPP5D, which results in a diminution of IgE-mediated degranulation in mast cells. No ligands have been identified for this molecule.