VPREB1 anticorps (PE)

N° du produit ABIN2662481

Détail du produit anti-VPREB1 anticorps (PE)

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp VPREB1 est conjugé à/à la PE

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: R3

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur VPREB1

Antigène: VPREB1 (Pre-B Lymphocyte 1 (VPREB1))

Autre désignation: CD179a (VPREB1 Produits)

Synonymes: anticorps IGI, anticorps IGVPB, anticorps VPREB, anticorps VpreB, anticorps CD179a, anticorps Vpreb-1, anticorps V-set pre-B cell surrogate light chain 1, anticorps immunoglobulin iota chain, anticorps immunoglobulin iota chain-like, anticorps pre-B lymphocyte 1, anticorps pre-B lymphocyte gene 1, anticorps VPREB1, anticorps LOC698810, anticorps LOC486411, anticorps Vpreb1

Sujet: CD179a, also known as VpreB, is an 18 kD member of the Ig superfamily, with an Ig V-like domain structure (that lacks the β strand of a typical V domain). CD179a associates with CD179b to form a surrogate light (SL) chain, which associates with the IgM heavy chain and the CD79a/CD79b heterodimer to form the pre-B cell receptor (PreBCR) complex. The function of CD179a/CD179b is still under investigation, though it has been reported that deficiency of CD179a and/or CD179b impairs the maturation of the B cell precursors beyond the pre-B cell stage.

Pathways: Production of Molecular Mediator of Immune Response, Regulation of Cell Size