BST2 anticorps (PE)
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- Antigène Voir toutes BST2 Anticorps
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp BST2 est conjugé à/à la PE
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Application
- Flow Cytometry (FACS), Immunocytochemistry (ICC), Intracellular Flow Cytometry (ICFC)
- Réactivité croisée
- Pigtailed Macaque, Macaque rhésus
- Purification
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
- Clone
- RS38E
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product BST2 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Protect from prolonged exposure to light. Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Antigène
- BST2 (Bone Marrow Stromal Cell Antigen 2 (BST2))
- Autre désignation
- CD317 (BST2 Produits)
- Synonymes
- anticorps BST2, anticorps CD317, anticorps TETHERIN, anticorps 2310015I10Rik, anticorps Bst-2, anticorps C87040, anticorps DAMP-1, anticorps GREG, anticorps Damp1, anticorps bone marrow stromal cell antigen 2, anticorps bone marrow stromal antigen 2, anticorps BST2, anticorps LOC618737, anticorps Bst2
- Sujet
- CD317, also known as BST2, Tetherin, and HM1.24, is a type II transmembrane GPI-protein with a molecular weight of about 29-33 kD. It is an interferon-induced protein expressed on dendritic cells, plasma cells, B lymphoblast cells, monocytes, granulocytes, T cells, NK cells, stromal cells, and some non-hematopoietic cells. BST2 inhibits cytokine production through interaction with ILT7 (CD85g). It is also involved in the regulation of B cell growth. More importantly, BST2 has been found to restrict the release of a number of viruses from infected cells, including all tested retroviruses (such as HIV-1) and some arenaviruses and filoviruses. In HIV-1 studies, it has been reported that BST2 retains the nascent virons on the surface of infected cells by incorporation of the protein into HIV-1 particles. HIV-1 Vpu is able to induce BST2 degradation.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response
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